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The global label-free detection market was valued at USD 402.8 million in 2020 and is projected to grow at a CAGR of 7.4% during the forecast period. Factors driving the growth of the label-free detection market include high sensitivity of label-free technologies, introduction of scientifically advanced products and growing spending on research and development by biotech and pharmaceutical companies.
Label-free binding assays enable analysis of biomolecular interactions using conditions close to native biological conformations, faster assay design, development and reagent preparation via use of unmodified reagents and substrates, more robust assay signals with less interference from fluorescent or other reporters, direct monitoring of binding complex formation, as secondary detection reagents aren’t needed to establish binding responses.
Regionally, North America accounted for the largest market share of the global label-free detection market attributable to the existence of major players. Leading players of the global label-free detection market include Bio-Rad Laboratories, Bioptix, General Electric, Attana, Corning, Inc., Ametek, Inc., Pall Corporation, X-body Biosciences, Danaher Corporation, Roche Diagnostics among others.
Key segments of the global label-free detection market
Product Overview, 2018-2028 (USD Million)
Technology Overview, 2018-2028 (USD Million)
Application Overview, 2018-2028 (USD Million)
End User Overview, 2018-2028 (USD Million)
Regional Overview, 2018-2028 (USD Million)
Reasons for the study
What does the report include?
Who should buy this report?
The myriad of technologies now available to researchers allows for label-free methods to impact drug development from early discovery to entry into the clinic and beyond. However, each of these methods comes with its own advantages and disadvantages. While many of these methods can be used at several stages of drug discovery and development, researchers may find any individual technology lacking either the throughput, sensitivity, or the ease of use that they may require. In addition, each method requires that can be used in the design and analysis of the experiments to ensure quality data are obtained. However, by combining several technologies one can leverage the strengths of the individual technology while avoiding the pitfalls.
On the basis of technology, the market is segmented into surface plasmon resonance, bio-layer interferometry, differential scanning calorimetry, isothermal titration calorimetry, and other label-free detection technologies. The surface plasmon resonance segment dominated the market in 2020.
Surface plasmon resonance (SPR) sensing has been demonstrated in the past decade to be an exceedingly powerful and quantitative probe of the interactions of a variety of biopolymers with various ligands, biopolymers, and membranes, including protein:ligand, protein:protein, protein:DNA and protein: membrane binding. It provides a means not only for identifying these interactions and quantifying their equilibrium constants, kinetic constants and underlying energetics, but also for employing them in very sensitive, label-free biochemical assays
As an early adopter of new technology in the electronics, nuclear and space exploration industries, the US has a pivotal role in setting label-free detection that has now been adopted and harmonized across the globe. It is the world's largest medical device market, has a massive pharmaceutical and biological manufacturing sector, and is at the forefront of nanotechnology research and developing technology for the next generation of wafers and chips. Europe also has one of the strongest and most productive life sciences industries in the world. There is a significant opportunity in label-free detection to be grasped, with global health and life science markets predicted to grow up to 10% per annum in the next decade.
The global label-free detection market was valued at USD 402.8 million in 2020 and is projected to grow at a CAGR of 7.4% during the forecast period. Factors driving the growth of the label-free detection market include high sensitivity of label-free technologies, introduction of scientifically advanced products and growing spending on research and development by biotech and pharmaceutical companies.
Label-free binding assays enable analysis of biomolecular interactions using conditions close to native biological conformations, faster assay design, development and reagent preparation via use of unmodified reagents and substrates, more robust assay signals with less interference from fluorescent or other reporters, direct monitoring of binding complex formation, as secondary detection reagents aren’t needed to establish binding responses.
Regionally, North America accounted for the largest market share of the global label-free detection market attributable to the existence of major players. Leading players of the global label-free detection market include Bio-Rad Laboratories, Bioptix, General Electric, Attana, Corning, Inc., Ametek, Inc., Pall Corporation, X-body Biosciences, Danaher Corporation, Roche Diagnostics among others.
Key segments of the global label-free detection market
Product Overview, 2018-2028 (USD Million)
Technology Overview, 2018-2028 (USD Million)
Application Overview, 2018-2028 (USD Million)
End User Overview, 2018-2028 (USD Million)
Regional Overview, 2018-2028 (USD Million)
Reasons for the study
What does the report include?
Who should buy this report?
1. Introduction
1.1. Introduction to the Study
1.2. Market Definition and Scope
1.3. Units, Currency, Conversions and Years Considered
1.4. Key Stakeholders
1.5. Key Questions Answered
2. Research Methodology
2.1. Introduction
2.2. Data Capture Sources
2.2.1. Primary Sources
2.2.2. Secondary Sources
2.3. Market Size Estimation
2.4. Market Forecast
2.5. Data Triangulation
2.6. Assumptions and Limitations
3. Executive Summary
4. Market Outlook
4.1. Introduction
4.2. Market dynamics
4.2.1. Drivers
4.2.2. Restraints
4.2.3. Opportunities
4.3. Porter’s five forces analysis
4.4. Value chain analysis
4.5. COVID-19 impact analysis
5. Label-Free Detection Market by Product, 2018-2028 (USD Million)
5.1. Introduction
5.2. Instruments
5.3. Consumables
6. Label-Free Detection Market by Application, 2018-2028 (USD Million)
6.1. Introduction
6.2. Binding kinetics
6.3. Hit confirmation
6.4. Lead generation
6.5. Endogenous receptor detection
6.6. Binding thermodynamics
6.7. Others
7. Label-Free Detection Market by Technology, 2018-2028 (USD Million)
7.1. Introduction
7.2. Surface plasmon resonance
7.3. Bio-layer interferometry
7.4. Differential scanning calorimetry
7.5. Isothermal titration calorimetry
7.6. Others
8. Label-Free Detection Market by End-use, 2018-2028 (USD Million)
8.1. Introduction
8.2. Pharmaceutical & biotechnology companies
8.3. Academic & research institutes
8.4. Contract research organizations
8.5. Others
9. Label-Free Detection Market by Region, 2018-2028 (USD Million)
9.1. North America
9.1.1. U.S.
9.1.2. Canada
9.2. Europe
9.2.1. UK
9.2.2. France
9.2.3. Germany
9.2.4. Rest of Europe
9.3. Asia Pacific
9.3.1. China
9.3.2. Japan
9.3.3. India
9.3.4. Rest of Asia Pacific
9.4. South America
9.5. Middle East and Africa
10. Competitive Landscape
10.1. Introduction
10.2. Strategic initiatives
10.2.1. Mergers & acquisitions
10.2.2. New product launch
10.2.3. Investments
10.2.4. Expansion
10.2.5. Others
11. Company Profiles
(Overview, Products and Services Portfolio, Recent Initiatives, Company Financials)
11.1. Bio-Rad Laboratories
11.2. Bioptix
11.3. General Electric
11.4. Attana
11.5. Corning, Inc.
11.6. Ametek, Inc.
11.7. Pall Corporation
11.8. X-body Biosciences
11.9. Danaher Corporation
11.10. Roche Diagnostics