During the forecast period, the l-hydroxyproline market is anticipated to expand at a noteworthy CAGR. The anti-wrinkle and collagen-boosting qualities of l-hydroxyproline, which make it a perfect element for cosmetics and nutritional supplements, are the main market-driving factors. The l-hydroxyproline market is also predicted to develop during the forecast period due to its expanding use as a taste enhancer in the food industry. Additionally, it is anticipated that rising consumer demand for healthy food items will support market expansion.
Furthermore, it is predicted that the market would increase during the forecast period due to rising consumer awareness of the advantages of l-hydroxyproline and rising demand for skin care products in emerging economies.
The food, pharmaceutical, and cosmetics sectors all employ l-hydroxyproline for a number of purposes. It is a common addition to a variety of goods, such as soups, sodas, dairy-based drinks, and conditioners for bread dough. L-hydroxyproline contributes to these goods' improved texture and flavour. It can also be utilised in various products as an antioxidant and preservative.
As a result, it has gained popularity due to its advantages in the food, pharmaceutical, and cosmetics industries. Additionally, because of its special qualities that are advantageous for skin health, its use is expanding. Last but not least, research is being done on L-hydroxyproline as a possible treatment for a number of ailments, including Parkinson's disease and Alzheimer's disease.
Proline is the source of the non-protein amino acid L-hydroxyproline. It is biosynthesized in the liver and is crucial for the production of collagen. About 10% of the amino acids in collagen are hydroxyprolines, which give this protein its stability and toughness. By increasing hydroxyproline levels through food and supplements, one can enhance the condition and appearance of one's skin and joints.
By 2031, the market for L-hydroxyproline is expected to have grown at a compound annual growth rate (CAGR) of 7.2%, reaching a value of USD 6.5 billion.
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Collagen, which is abundantly present in connective tissues like cartilage and tendons that surround muscles and bones, contains L-hydroxyproline, an important component. This amino acid can be produced from hydroxylysine or obtained through various procedures from sources such as food and natural goods.
The market's expansion is anticipated to be constrained by a few restraints. The usage of L-hydroxyproline in cosmetics and food items is subject to strict rules, and the price of L-hydroxyproline of pharmaceutical grade is one of these impediments. The FDA, EMA, and CosIng are just a few of the government agencies that control L-hydroxyproline. L-hydroxyproline usage in cosmetics is capped at 0.3% by CosIng. Additionally, it is classified as a permitted ingredient for use in cosmetic goods up to a maximum concentration of 0.5% in Annex II of the European Cosmetic Directive 76/768/EEC. A few restraints are projected to limit the market's growth. The cost of L-hydroxyproline of pharmaceutical grade is one of the restrictions on the use of this amino acid in food and cosmetic products. L-hydroxyproline is regulated by a number of governmental organisations, including the FDA, EMA, and CosIng. CosIng limits the amount of L-hydroxyproline used in cosmetics to 0.3%.
Additionally, it is listed in Annex II of the European Cosmetic Directive 76/768/EEC as a permitted ingredient for use in cosmetic products up to a maximum concentration of 0.5%. During the anticipated period, these regulations are anticipated to impede the market's expansion for L-hydroxyproline. Additionally, pharmaceutical grade L-hydroxyproline is more expensive than other grades like industrial grade and cosmetics grade because it is produced using a synthetic procedure. However, the price is anticipated to drop soon due to the rising demand for L-hydroxyproline in medicines.
Merck KGaA, Wacker Chemie AG, Pfizer Inc., Evonik Industries AG, and Lianyungang Shenyu Pharmaceutical Co. Ltd. are a few of the major producers active in the global L-hydroxyproline market. Additionally, the industry is also home to a large number of additional small and medium-sized businesses. Additionally, some regional and local players are increasingly concentrating on enhancing their product lines in order to take advantage of the rising demand for L-hydroxyproline globally.
Segment Analysis
The Pharmaceutical Grade Sector emerged as the Most Lucrative Type
The pharmaceutical grade sector, which accounts for about 60% of the market, has the biggest share of all types, followed by industrial grade, which accounts for about 40%. Due to its greater purity relative to other accessible grades and favourable safety profile, pharmaceutical grade L-hydroxyproline is frequently used in pharmaceutical products and dietary supplements. The dietary grade is expected to experience strong demand over the projected period due to its many advantages, including enhanced skin and hair health
The Most Prominent Application is the Dietary Supplements Segment
The market is anticipated to be dominated by dietary supplements with a share of more than 60%. The inclusion of L-hydroxyproline into dietary supplements such as powders and beverages will continue to drive demand throughout the forecast period, despite the fact that it is accessible in a variety of formats, including tablets and capsules.
The Asia Pacific Region to render Ample Financing Opportunities
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa comprise the other regional segments of the global L-hydroxyproline market. Due to the size of its nutraceuticals and cosmetics sector, North America has a major market share worldwide. The next region is the European one, which has a significant number of important businesses working there. Due to growing consumer awareness of the health benefits of this product, the Asia Pacific region is anticipated to have the quickest growth throughout the projection period.
COVID-19 Impact and Market Status
The COVID-19 pandemic epidemic has had a substantial effect on the L-hydroxyproline market. Due to the downturn in economic activity and constraints on foreign trade, a fall in demand is anticipated in the market. Additionally anticipated to have an impact on the industry is the decreased output of pharmaceuticals and cosmetics brought on by the closure of manufacturing facilities. Market recovery is anticipated in 2021 when economic activity increases and trade barriers are removed.
Recent Developments in the L-Hydroxyproline Market
• A new pharmaceutical product based on L-hydroxyproline received marketing authorization approval from the European Commission in January 2021. (LHP). The medication, known as Proleva, was created by Hospira Italia S.p.A. and is meant to be used as a treatment for adult individuals with Duchenne muscular dystrophy who have previously had scoliosis as a result of the condition.
• A study that examined the effects of L-hydroxyproline supplementation on bone strength and integrity in post-menopausal women was also published in February 2021. Results revealed that LHP could lessen risk factors for osteoporosis and enhance biomechanical metrics related to bone fragility.
• A Japanese food supplement firm released a novel nutraceutical in February 2020 with L-hydroxyproline and other natural ingredients with the aim of enhancing joint health.
• According to a new Frost & Sullivan analysis published in May 2020, the Asia Pacific region will experience the fastest rate of growth in the LHP market because of rising demand from a variety of end-use industries, including medicines and dietary supplements.
L-Hydroxyproline Market Scope
| Metrics | Details |
| Base Year | 2023 |
| Historic Data | 2018-2022 |
| Forecast Period | 2024-2031 |
| Study Period | 2018-2031 |
| Forecast Unit | Value (USD) |
| Revenue forecast in 2031 | USD 6.5 billion |
| Growth Rate | CAGR of 7.2 % during 2022-2031 |
| Segment Covered | Type, Application, Regions |
| Regions Covered | North America, Europe, Asia Pacific, South America, Middle East and Africa |
| Key Players Profiled | Merck KGaA, Wacker Chemie AG, Pfizer Inc., Evonik Industries AG, and Lianyungang Shenyu Pharmaceutical Co. Ltd. |
Key Segments of the L-Hydroxyproline Market
Type Overview, (USD Billion)
• Pharmaceutical Grade
• Industrial Grade
Application Overview, (USD Billion)
• Pharmaceutical Intermediate
• Cosmetics
• Food
• Dietary Supplement
• Others
Regional Overview, (USD Billion)
North America
• U.S
• Canada
Europe
• Germany
• France
• UK
• Rest of Europe
Asia Pacific
• China
• India
• Japan
• Rest of Asia Pacific
South America
• Mexico
• Brazil
• Rest of South America
• Middle East and South Africa
Frequently Asked Questions (FAQ) :
The global L-Hydroxyproline market size is expected to reach USD 6.5 billion and CAGR of 7.2 % during 2021-2031