Global burden of untreated medical needs and diseased population continue to remain major healthcare deterrents in recent years. International organizations such as WHO is propelling novel mandates and funding assistance to leverage deep-seeded pharmaceutical endeavors especially towards drug development. Under these prevailing circumstances high throughput screening is witnessing large scale adoption and advances to enable novel breakthroughs. Several technological assays are underway to assist high throughput screening. A variety of high throughput screening methodologies such as cell-based assays, microbial cell cultures that have contributed towards innovations in nanoliter volumes and ultrasensitive biosensors that are beneficial for high throughput screening performed across nanoliter and picoliter capacities.
High validation of high throughput screening protocols are exceptionally desirable for successful strides in drug discovery. Scientists and think tank fraternity are engaging in developing advanced mechanism to accelerate high throughput screening. In a recent development, Ncardia which is essentially a leader in contract research organization focusing mainly on drug discovery has come up with a novel approach to carry out mega scale cell culturing on automated platforms. The development is a crucial breakthrough in fueling stability and growth in global high throughput screening market.
High throughput screening is essentially an advanced testing mechanism that enables parallel testing of voluminous samples with exceptional efficiency in considerably short duration to pursue drug discovery. High throughput screening involves detailed analytical assessment and study of micro dimensional molecules and compounds that have significant bearing on the efficacy of the clinical study of drugs. Under these prevailing conditions, adequate modes of dispensing of reagents in liquified form attains crucial importance that necessitates extensive miniaturisation of high throughput screening for high content research developments. Liquid dispensing thus becomes prominently vital to pursue drug discovery experiments in amicro chips as well as medium and high density plates.
High throughput screening methodologies are high end tactics employed exclusively for scientific experimentation related to drug discovery initiatives with the help of advanced processes such as data processing, robotics, liquid handling devices and detectors. Collaboration of these high technologies allows researchers to use high throughput screening mechanism to perform several genetic, biochemical and pharmacological tests to accurately identify active compounds, genes as well as antibodies to establish a biomolecular roadmap, for successful enablement of drug design. high potency with negligible chances of errors coupled with tremendous speed and accuracy sets large scale reliance on high throughput screening practices.